Individual Test

Private Syphilis RPR/VDRL Test London

RPR and VDRL tests measure disease activity in syphilis. Used to monitor treatment response and check for reinfection.

20 min appointment
Results: 2 days"
Confidential
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Price

£46

+ £50 blood draw

  • Report within 2 days"
  • Completely private, results go to you only
  • No GP referral required
  • Calm, discreet Marylebone clinic
  • Secure portal delivery of results
  • Appointments led by registered nurses

Private Syphilis RPR Test in London

Wimpole Street Medical & Dental offers private RPR (Rapid Plasma Reagin) testing for syphilis at our clinic. RPR is a non-treponemal test that measures disease activity and response to treatment.

Testing requires a venous blood sample, with results available within 2 days. (includes £50 phlebotomy fee).

No GP referral is required. All samples are processed at UKAS-accredited laboratories. Results are communicated confidentially.

Understanding RPR Testing

RPR is a non-treponemal test that detects antibodies produced in response to tissue damage caused by Treponema pallidum. Unlike treponemal tests (EIA, TPHA), RPR titres correlate with disease activity and decline following successful treatment.

RPR is typically used alongside treponemal tests. A positive treponemal screening test followed by a quantitative RPR helps determine whether syphilis is active, recently treated, or historic. Serial RPR monitoring after treatment confirms adequate treatment response.

Clinical Uses of RPR

Disease activity assessment

High RPR titres suggest active, untreated syphilis.

Treatment monitoring

A four-fold decline in titre indicates successful treatment.

Reinfection detection

A four-fold rise in titre may indicate reinfection.

Staging support

RPR results help differentiate between stages of syphilis.

Monitor Disease Activity

RPR/VDRL tests help track syphilis activity and treatment response.

  • Measures disease activity
  • Monitors treatment success
  • Detects reinfection
  • Quantitative results
  • Important follow-up test

Discretion Guaranteed

Results shared with you alone

Prompt Turnaround

Report within 2 days"

Nurse-Led Appointments

Registered nurses, zero judgement

Laboratory Analysis

Samples processed by partner labs

What to Expect, Start to Finish

1

Reserve Online

Pick a slot that suits your schedule

2

Come to Wimpole Street

A short, private visit in Marylebone

3

Sample Taken

Collected gently by a registered nurse

4

Report Delivered

Sent securely within 2 days"

Frequently Asked Questions

RPR/VDRL measure disease activity and decrease after treatment, unlike treponemal antibodies which stay positive.

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Take the First Step Today

Reserve a discreet appointment at our Marylebone clinic, your report follows within 2 days".

020 7183 0692

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Meet Our Medical Team

Our experienced medical team is fully qualified and registered with the GMC and NMC, delivering safe, high-quality care in line with the highest professional standards.
Because our patients deserve nothing less.

Registered. Regulated. Trusted.

At Wimpole Street Medical & Dental, our clinicians are registered with the relevant UK regulatory bodies, including the GDC, GMC and NMC. Our dentists, dental nurses and medical professionals deliver care that meets the highest clinical, safety and ethical standards, because our patients deserve nothing less.

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We Accept All Major Dental Insurances

We accept all major UK dental insurances, including AXA PPP Healthcare Dental Cover, Aviva Dental Insurance, Bupa Dental Cover, Cigna Dental Insurance, Vitality Dental Health Insurance, Unum and Boots Dental Plan Cover. We provide itemised receipts so you can claim back your treatment costs.

Aviva Dental Insurance accepted at Wimpole Street Medical & Dental
AXA PPP Healthcare Dental Cover accepted at Wimpole Street Medical & Dental
Bupa Dental Cover accepted at Wimpole Street Medical & Dental
Cigna Dental Insurance accepted at Wimpole Street Medical & Dental
Vitality Dental Health Insurance accepted at Wimpole Street Medical & Dental
Unum Dental Cover accepted at Wimpole Street Medical & Dental
Boots Dental Plan Cover accepted at Wimpole Street Medical & Dental
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Opening 1 November 2026
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