Private Hereditary Neuropathy with Liability to Pressure Palsy - PMP22 deletion analysis Blood Test London
Hereditary Neuropathy with Liability to Pressure Palsy - PMP22 deletion analysis to detect genetic markers and guide diagnosis. Referral from clinical neurologist or clinical geneticist required.
Hereditary Neuropathy with Liability to Pressure Palsy - PMP22 deletion analysis
Test fee £680 + £50 phlebotomy fee (per visit)
- Results in 6 weeks"
- UKAS accredited laboratory
- Professional phlebotomy service
- Confidential results portal
Genetic Test — Lab Approval Required
This genetic test is subject to referral acceptance by our partner laboratory. After you book, our team will contact you to collect your full medical history and obtain the laboratory's acceptance before your appointment is confirmed. For this reason, appointments must be booked at least 2 days in advance. Your booking remains provisional until confirmed — no payment is taken when booking, and if the laboratory is unable to accept the referral, no sample is taken and nothing is charged.
Specialist referral required — 020 7183 0692
Pay at clinic on the day of your appointment
Hereditary Neuropathy with Liability to Pressure Palsy - PMP22 deletion analysis – Private Testing in London
The Hereditary Neuropathy with Liability to Pressure Palsy (HNPP) PMP22 deletion analysis is available at Wimpole Street Medical and Dental, our CQC-registered clinic in Marylebone, London W1G. This test is priced at £680. A £50 phlebotomy fee applies per visit for blood collection. It requires a venous blood sample, and results are typically available within 6 weeks. A referral from a clinical neurologist or clinical geneticist is required before this test can be ordered.
HNPP is an autosomal dominant inherited neuropathy caused by a deletion of one copy of the PMP22 gene on chromosome 17p. It is the reciprocal genetic change to the CMT1A duplication. HNPP causes recurrent episodes of numbness, weakness, and muscle atrophy triggered by minor pressure or trauma to peripheral nerves.
Specialist Referral Required
This test requires a referral from a clinical neurologist or clinical geneticist before it can be ordered. Please bring your referral letter to your appointment or email it to wimpolestreet@md.co.uk in advance.
Booking online: your appointment is provisional. Before your visit, our team will contact you to collect your full medical history and obtain acceptance from our partner laboratory. For this reason, the earliest bookable date is 2 days ahead — same-day and next-day appointments are not available for this test. No payment is taken when booking; if the laboratory does not accept the referral, no sample is taken and nothing is charged.
Questions? Call us on 020 7183 0692 — we're happy to help.
Who Should Consider HNPP PMP22 Deletion Testing?
Individuals with recurrent, painless episodes of focal weakness or sensory loss affecting individual nerves, particularly at common compression sites such as the elbow (ulnar nerve), wrist (median nerve), or fibular head (peroneal nerve). Those with nerve conduction studies showing conduction block or focal slowing at entrapment sites with background mild generalised slowing.
HNPP follows autosomal dominant inheritance. Each child of an affected individual has a 50% chance of inheriting the deletion. Genetic counselling is recommended to discuss the implications for the individual and family members.
A trained nurse collects the blood sample by standard venepuncture at our clinic on Wimpole Street, directly opposite Wimpole Street tube station (Piccadilly, Circle, and District lines). A referral from a clinical neurologist or clinical geneticist is required — please call 020 7183 0692 to arrange.
Autoimmune Assessment
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How It Works
Book Online
Choose a convenient date and time
Visit Our Clinic
22 Wimpole Street, Wimpole Street
Quick Blood Draw
Professional phlebotomy, 5 minutes
Get Results
Results in 6 weeks"
Frequently Asked Questions
Common questions about this blood test
Visit Our London Clinic
Central London location with excellent transport links
Address
Wimpole Street Medical & Dental
22 Wimpole Street
Wimpole Street
London W1G 8GQ
Getting Here
- 2-minute walk from Wimpole Street tube
- Circle, District & Piccadilly lines
Opening Hours
- Monday, Wednesday9am - 6pm
- Tuesday, Thursday9am - 8pm
- Friday8am - 5pm
- Saturday10am - 4pm
- Sunday10am - 4pm
Contact
Ready to Book Your Test?
A specialist referral is required for this test. Book online (provisional — our team will confirm laboratory acceptance before your visit) or call us. Results within 6 weeks".
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Meet Our Medical Team
Our experienced medical team is fully qualified and registered with the GMC and NMC, delivering safe, high-quality care in line with the highest professional standards.
Because our patients deserve nothing less.
Registered. Regulated. Trusted.
At Wimpole Street Medical & Dental, we are in the process of registering with the Care Quality Commission (CQC) and our clinicians are registered with the relevant UK regulatory bodies, including the GDC and GMC. Our dentists, dental nurses and medical professionals deliver care that meets the highest clinical, safety and ethical standards, because our patients deserve nothing less.
