Private CADASIL - NOTCH3 gene sequencing Blood Test London
CADASIL - NOTCH3 gene sequencing is a private test offered at our clinic in Marylebone, London. It should be ordered and interpreted by a registered clinician based on your symptoms and clinical context.
CADASIL - NOTCH3 gene sequencing
Test fee £1200 + £50 phlebotomy fee (per visit)
- Results in 6 weeks"
- UKAS accredited laboratory
- Professional phlebotomy service
- Confidential results portal
Or call 020 7183 0692
Pay at clinic on the day of your appointment
CADASIL - NOTCH3 gene sequencing – Private Testing in London
The CADASIL - NOTCH3 gene sequencing is available at Wimpole Street Medical and Dental, our clinic in Marylebone, London W1G. This test is priced at £1200. A £50 phlebotomy fee applies per visit for blood collection. It requires a venous blood sample, and results are typically available within 6 weeks.
This is a next-generation sequencing (NGS) panel that analyses multiple genes simultaneously to detect variants associated with CADASIL. NGS technology can identify single nucleotide variants and small insertions or deletions across all targeted genes in one test.
Who Should Consider the CADASIL - NOTCH3 gene sequencing?
Individuals with clinical features suggestive of CADASIL, or a family history of the condition. Patients referred by a specialist for genetic confirmation. Couples planning a family who wish to understand carrier status for inherited conditions.
Genetic testing results may have implications for biological relatives. Pre-test genetic counselling is recommended to ensure informed consent. Variants of uncertain significance (VUS) may be identified and require careful interpretation.
A trained nurse collects the blood sample by standard venepuncture, a straightforward procedure that typically takes around five minutes. Our clinic is on Wimpole Street, a short walk from Bond Street and Oxford Circus stations. No GP referral is needed, book online or call 020 7183 0692.
Genetic Investigation
CADASIL - NOTCH3 gene sequencing provides genetic information that should be ordered alongside appropriate genetic counselling and clinical assessment.
- Family history of the condition
- Personal symptoms suggestive of the condition
- Confirmation of a clinical diagnosis
- Carrier or reproductive risk assessment
- Specialist clinical genetics workup
- Clinician-directed testing
Your Appointment, Step by Step
Reserve Online
Pick a date and time that fits your diary
Come to Marylebone
22 Wimpole Street, near Bond Street & Oxford Circus
Sample Taken by a Nurse
A brief, gentle blood draw, around 5 minutes
Report Delivered Securely
Results in 6 weeks"
Frequently Asked Questions
What patients most often want to know before this test
Find Us in Marylebone
In the heart of London's Harley Street medical district, moments from Oxford Street
Address
Wimpole Street Medical & Dental
22 Wimpole Street
Marylebone
London W1G 8GQ
Getting Here
- Short walk from Bond Street station (Elizabeth, Central & Jubilee lines)
- Oxford Circus (Victoria, Central & Bakerloo lines) also nearby
Opening Hours (from 1 October 2026)
- Monday, Wednesday9am - 6pm
- Tuesday, Thursday9am - 8pm
- Friday8am - 5pm
- Saturday10am - 4pm
- SundayClosed
Contact
Arrange Your Test in Marylebone
You won't need a GP referral, simply reserve a slot online and visit us at 22 Wimpole Street. Your report follows within 6 weeks".
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Meet Our Medical Team
Our experienced medical team is fully qualified and registered with the GMC and NMC, delivering safe, high-quality care in line with the highest professional standards.
Because our patients deserve nothing less.
Registered. Regulated. Trusted.
At Wimpole Street Medical & Dental, our clinicians are registered with the relevant UK regulatory bodies, including the GDC, GMC and NMC. Our dentists, dental nurses and medical professionals deliver care that meets the highest clinical, safety and ethical standards, because our patients deserve nothing less.
We Accept All Major Dental Insurances
We accept all major UK dental insurances, including AXA PPP Healthcare Dental Cover, Aviva Dental Insurance, Bupa Dental Cover, Cigna Dental Insurance, Vitality Dental Health Insurance, Unum and Boots Dental Plan Cover. We provide itemised receipts so you can claim back your treatment costs.











